METHOD FOR PREDICTION OF PROGNOSIS BY HUMAN PAPILLOMAVIRUS DNA INTEGRATION PATTERN

摘要

Provided is a method for analyzing the prognosis of cervical cancer according to the human papillomavirus (HPV) DNA integration pattern. The method of analyzing the prognosis of cervical cancer according to the human papillomavirus DNA integration pattern of the present invention enables an observation of the HPV DNA integration pattern with accuracy and convenience via in situ hybridization (ISH) compared to qPCR analysis. Since the prognosis of cervical cancer having the tumors with an episomal pattern and an integrated pattern can be significantly distinguished when the HPV DNA integration patterns are classified by the above method, the survival rate after radiotherapy of cervical cancer, and in particular invasive cervical cancer, can be more accurately analyzed.

主权项

1. A method for analyzing the prognosis of cervical cancer, comprising:
obtaining tumor tissues from cervical cancer patients and observing the of human papillomavirus DNA integration pattern by in situ hybridization (ISH); and predicting the prognosis of cervical cancer according to the human papillomavirus DNA integration pattern.