| 发明名称 |
CYSTEINE VARIANTS OF INTERLEUKIN-11 AND METHODS OF USE THEREOF |
| 摘要 |
Disclosed are cysteine variants of interleukin-11 (IL-11) and methods of making and using such proteins in therapeutic applications. |
| 申请公布号 |
US2016200790(A1) |
申请公布日期 |
2016.07.14 |
| 申请号 |
US201414262260 |
申请日期 |
2014.04.25 |
| 申请人 |
BOLDER BIOTECHNOLOGY, INC. |
发明人 |
Cox, III George N. |
| 分类号 |
C07K14/54 |
主分类号 |
C07K14/54 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method to treat an animal with a disease or condition that can be treated by wild-type interleukin-11 (IL-11), to stimulate platelet production in an animal, or to accelerate an animal's recovery from thrombocytopenia, comprising administering to the animal an interleukin-11 (IL-11) cysteine mutein, wherein the mutein has biological activity in vitro as measured by proliferation of a cell line that proliferates in response to IL-11. |
| 地址 |
Boulder CO US |
