Compositions containing ionic liquids and their uses, in particular in organic synthesis

摘要

An ionic liquid is used as liquid matrix for organic synthesis in homogeneous phase on soluble support, the ionic liquid being presented in liquid or solid form at ambient temperature, of formula A1+X1−, A1+ representing a cation, functional or non-functional, or a mixture of cations in which either none of the cations is functional or at least one of the cations is functional, and X1− an anion, functional or non-functional, or a mixture of anions in which either none of the anions is functional or at least one of the anions is functional.

主权项

1. A method of performing a Heck coupling reaction in a homogeneous phase on a soluble reaction support, without volatile organic solvents, comprising:
(i) dissolving a soluble reaction support in the form of a functionalized onium salt in a liquid matrix in the form of a ionic liquid of formula A1+X1− to form a composition, wherein said ionic liquid of formula A1+X1− is not functionalized; (ii) adding at least one reagent to the composition obtained in step (i); and (iii) converting the chemical function(s) of said functionalized onium salt to provide a Heck coupling on the soluble reaction support, without volatile organic solvents, wherein, said non-functionalized ionic liquid of formula A1+X1− is in liquid or solid form at ambient temperature, A1+ is a non organic-functional cation or a mixture of non organic-functional cations, and X1− a non organic-functional anion or a mixture of non organic-functional anions.