摘要 |
This invention relates to optically active 2-(disubstituted aryl) cyclopropane carboxamide derivatives which are useful intermediates for the preparation of pharmaceutical agents, and in particular the compound [1 S -(1±, 2±, 3² (1 S *,2 R *),5²)]-3-[7-[2-(3,4-difluorophenyl)-cyclopropyl]amino]-5-(propylthio)-3 H -1,2,3-triazolo[4,5- d ]pyrimidin-3-yl)-5-(2-hydroxyethoxy)-cyclopentane-1,2-diol. |