| 发明名称 |
LPS SEROTYPES FOR DETERMINING SEVERITY OF URINARY TRACT INFECTION |
| 摘要 |
A method of identifying a subject having a urinary tract infection posing a significant risk of dangerous sequalae is described. The method includes obtaining a urine or fecal sample from the subject; determining the predominant LPS O-antigen serotype in the sample; and comparing the predominant LPS O-antigen serotype to a set of febrile UTI LPS serotypes. The method can also include treating the subject for UTI if the predominant O-antigen LPS serotype is a febrile UTI LPS serotype. |
| 申请公布号 |
US2016312270(A1) |
申请公布日期 |
2016.10.27 |
| 申请号 |
US201615180352 |
申请日期 |
2016.06.13 |
| 申请人 |
RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL |
发明人 |
Justice Sheryl S.;Mason Kevin M. |
| 分类号 |
C12Q1/68;A61K39/02 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of identifying and treating a subject for a urinary tract infection (UTI) having a significant risk of dangerous sequalae, comprising:
obtaining a urine or fecal sample from the subject; determining the predominant LPS O-antigen serotype in the sample; comparing the predominant LPS O-antigen serotype to a set of febrile UTI LPS serotypes; and treating the UTI of the subject if the predominant O-antigen LPS serotype is a febrile UTI LPS serotype. |
| 地址 |
Columbus OH US |
