发明名称 |
A PHARMACEUTICAL FORMULATION OF AT LEAST ONE ROTIGOTINE SALT AND USES THEREOF |
摘要 |
The present invention relates to new salts of 6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1- ol (rotigotine), their use as a medicament, for example for the treatment of CNS disorders like Parkinson Disease, RLS, fybromyalgia and/or depres-sion, in particular through electromotive administration. The present invention relates to pharmaceutical formulations suitable for iontophoresis that provide enhanced iontophoretic delivery of rotigotine to at least one target tissue. The formulations are further characterized by good to excellent solubility of the salts in aqueous solutions. |
申请公布号 |
CA2761427(C) |
申请公布日期 |
2016.11.22 |
申请号 |
CA20102761427 |
申请日期 |
2010.06.24 |
申请人 |
UCB PHARMA GMBH |
发明人 |
BOUWSTRA, J.A.;ACKAERT, O.W.G.M.K.;EIKELENBOOM, J.;WOLFF, HANS-MICHAEL |
分类号 |
C07D333/20;A61K9/00;A61K31/381;A61P25/16 |
主分类号 |
C07D333/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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