主权项 |
1. A method of treating cancer in a subject in need thereof, said method comprising administering to the subject an effective amount of a compound having the formula: wherein R1 and R2 are independently hydrogen or substituted or unsubstituted alkyl; R3 is independently substituted or unsubstituted alkyl; R5 is independently halogen, —CN, —CXa3, —S(O)2H, —NO, —NO2, —C(O)H, —C(O)NH2, —S(O)2NH2, —OH, —SH, —SO2Cl, —SO3H, —SO4H, —NHNH2, —ONH2, —NHC═(O)NHNH2, —NHC═(O)NH2, —NHSO2H, —NHC═(O)H, —NHC(O)—OH, —NHOH, —OCF3, —OCHF2, —CO2H, or substituted or unsubstituted (C1-C6) alkyl; R6 is independently halogen, —CN, —CXb3, —S(O)2H, —NO, —NO2, —C(O)H, —C(O)NH2, —S(O)2NH2, —OH, —SH, —SO2Cl, —SO3H, —SO4H, —NHNH2, —ONH2, —NHC═(O)NHNH2, —NHC═(O)NH2, —NHSO2H, —NHC═(O)H, —NHC(O)—OH, —NHOH, —OCF3, —OCHF2, or —CO2H; L1 is independently a bond or substituted or unsubstituted alkylene; z1 is independently an integer from 0 to 4; z2 is independently an integer from 0 to 5; and Xa and Xb are independently —F, —Cl, —Br, or —I. |