Assymetric hydrogenation of furolimidazol derivatives.
摘要
<p>A novel process for the asymmetric hydrogenation of furoimidazole derivatives of the general formula <IMAGE> with hydrogen in the presence of a homogeneous catalyst to give the corresponding diastereomeric dihydrofuroimidazole derivatives of the general formula <IMAGE> is described. The dihydrofuroimidazole derivatives of the general formula (II) are intermediates for the preparation of the vitamin (+)-biotin.</p>
申请公布号
EP0624587(A3)
申请公布日期
1996.02.28
申请号
EP19940107390
申请日期
1994.05.11
申请人
LONZA A.G.
发明人
MCGARRITY, JOHN, DR.;SPINDLER, FELIX, DR.;FUCHS, RUDOLF, DR.;EYER, MARTIN, DR.