LIPOSOMALLY ENCAPSULATED REDUCED GLUTATHIONE, INCLUDING WITH OTHER PHARMACOLOGIC PREPARATION, CAPABLE OF ADMINISTRATION AS AN ORAL, TOPICAL, INTRAORAL OR TRANSMUCOSAL PREPARATION, FOR REVERSAL AND PREVENTION OF OXIDATION OF CHOLESTEROL AND OF LOW DEN

摘要

The invention proposes the use of reduced glutathione in a liposome (liposomal reduced glutathione) in form useable intravenously, orally, dermally or mucosally, for administration of a therapeutically effective amount to ameliorate the progression of vascular disease, including atherosclerosis, diabetes, hypertension, narrowing of arteries leading to decreased blood flow, ischemic events, and the formation of blood clots, abnormal platelet aggregation, and thrombotic events, by reducing the amount and effect of oxidized cholesterol, oxidized HDL and oxidized LDL. The invention also proposes combining liposomal encapsulated glutathione with statin drugs to improve the effect of lowering not only cholesterol but also the oxidized cholesterol as well as oxidized HDL and oxidized LDL. The invention proposes a combination with a nitrous oxide enhancing substance such as arginine or lysine. The invention also proposes combining liposomal encapsulated glutathione with CoQ10 and other hypertensive treatment drugs such as lisinopril and ACE inhibitors as a therapy for vascular disease and management of side effects of statin therapy.