VIP3 toxins and methods of use

摘要

Nucleic acid molecules encoding novel Vip3 toxins that are highly active against a wide range of lepidopteran insect pests are disclosed. The nucleic acid molecules can be used to transform various prokaryotic and eukaryotic organisms to express the Vip3 toxins. These recombinant organisms can be used to control lepidopteran insects in various environments.

主权项

1. A transgenic host cell comprising an expression cassette comprising a heterologous promoter operably linked to a nucleic acid encoding a toxin that is active against European corn borer, wherein said toxin comprises an amino acid sequence that has at least 97% sequence identity with SEQ ID NO: 2 and wherein the C-terminus of said toxin comprises amino acids 661-788 of SEQ ID NO: 2.