发明名称 |
Combinations of AKT inhibitor compounds and abiraterone, and methods of use |
摘要 |
The invention provides a combination of a) a compound of Formula (Ia): or a pharmaceutically acceptable salt thereof, and b) abiraterone or a pharmaceutically acceptable salt thereof for the prophylactic or therapeutic treatment of a hyperproliferative disorder, such as cancer.; |
申请公布号 |
US9346789(B2) |
申请公布日期 |
2016.05.24 |
申请号 |
US201214009316 |
申请日期 |
2012.03.30 |
申请人 |
Genentech, Inc. |
发明人 |
Nannini Michelle;Sampath Deepak |
分类号 |
A61K31/519;C07D239/70;C07D403/12;A61K31/437;A61K31/496;A61K31/517;A61K31/58;A61K31/282;A61K31/337;A61K31/4188;A61K31/4745;A61K31/513;A61K31/704;A61K39/395;A61K31/436;A61K31/138;A61K31/4166;A61K31/495;A61K31/555;A61K31/7068;C07K16/40;A61K39/00 |
主分类号 |
A61K31/519 |
代理机构 |
Viksnins Harris & Padys PLLP |
代理人 |
Viksnins Harris & Padys PLLP |
主权项 |
1. A combination of a) a compound of Formula Ia:or a pharmaceutically acceptable salt thereof, and b) abiraterone or a pharmaceutically acceptable salt thereof, or abiraterone acetate or a pharmaceutically acceptable salt thereof. |
地址 |
South San Francisco CA US |