发明名称 Combinations of AKT inhibitor compounds and abiraterone, and methods of use
摘要 The invention provides a combination of a) a compound of Formula (Ia): or a pharmaceutically acceptable salt thereof, and b) abiraterone or a pharmaceutically acceptable salt thereof for the prophylactic or therapeutic treatment of a hyperproliferative disorder, such as cancer.;
申请公布号 US9346789(B2) 申请公布日期 2016.05.24
申请号 US201214009316 申请日期 2012.03.30
申请人 Genentech, Inc. 发明人 Nannini Michelle;Sampath Deepak
分类号 A61K31/519;C07D239/70;C07D403/12;A61K31/437;A61K31/496;A61K31/517;A61K31/58;A61K31/282;A61K31/337;A61K31/4188;A61K31/4745;A61K31/513;A61K31/704;A61K39/395;A61K31/436;A61K31/138;A61K31/4166;A61K31/495;A61K31/555;A61K31/7068;C07K16/40;A61K39/00 主分类号 A61K31/519
代理机构 Viksnins Harris & Padys PLLP 代理人 Viksnins Harris & Padys PLLP
主权项 1. A combination of a) a compound of Formula Ia:or a pharmaceutically acceptable salt thereof, and b) abiraterone or a pharmaceutically acceptable salt thereof, or abiraterone acetate or a pharmaceutically acceptable salt thereof.
地址 South San Francisco CA US