| 发明名称 |
STABLE AQUEOUS PHARMACEUTICAL FORMULATION OF NATALYZUMAB AND METHOD FOR ITS OBTAINING |
| 摘要 |
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight. |
| 申请公布号 |
UA82685(C2) |
申请公布日期 |
2008.05.12 |
| 申请号 |
UA20050008632 |
申请日期 |
2004.02.09 |
| 申请人 |
ELAN PHARMACEUTICALS, INC. |
发明人 |
URKE DAVID J (US);BUCKLEY SHAUN E;CONOR BARBARA HORSEY O;LEHRMAN SHER WOOD RUSS;BCALLAWAY JAMES |
| 分类号 |
A61K39/395;A61K;A61K39/00;A61K39/38;A61K47/02;A61K47/08;C07K1/00;C07K16/28 |
主分类号 |
A61K39/395 |
| 代理机构 |
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