发明名称 |
NATURAL-KILLER/T-CELL LYMPHOMA (NKTCL) SUSCEPTIBILITY PREDICTION, DIAGNOSIS AND THERAPY |
摘要 |
Natural-Killer T-Cell Lymphoma (NKTCL) susceptibility prediction, diagnosis and therapy. The invention relates to a method for predicting Natural Killer T-cell Lymphoma (NKTCL) susceptibility and/or diagnosing NKTCL in a subject comprising testing for JAK mutations. The invention also relates to a method of screening for candidate agents capable of treating NKTCL using a cell line comprising at least one JAK mutation. The invention includes an NKTCL animal model comprising at least one JAK mutation. The invention also includes JAK inhibitors for treating NKTCL. |
申请公布号 |
SG10201605729T(A) |
申请公布日期 |
2016.08.30 |
申请号 |
SGT10201605729 |
申请日期 |
2012.11.26 |
申请人 |
SINGAPORE HEALTH SERVICES PTE LTD |
发明人 |
TEH, BIN TEAN;LIM, SOON THYE |
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