发明名称 HUMAN M-CSF ANTIBODY AND DETERMINATION OF HUMAN M-CSF
摘要 <p>PURPOSE:To provide the subject new antibody specifically reacting with human macrophage colony stimulation factor and capable of accurately determining the factor in a specimen in high sensitivity even at a low concentration. CONSTITUTION:The objective antibody specifically reacts with human macrophage colony stimulation factor (human M-CSF). The antibody can be produced by immunizing a mammal such as mouse with human M-CSF (derivative) as an immunogen, fusing the plasmacytic cell (preferably spleen cell) of the immunized animal to a plasmacytoma cell of a mammal to form a hybridoma, selecting a clone producing the desired antibody from the hybridoma and cultivating the clone.</p>
申请公布号 JPH0595794(A) 申请公布日期 1993.04.20
申请号 JP19910324972 申请日期 1991.10.04
申请人 OTSUKA PHARMACEUT CO LTD 发明人 OMOTO YASUKAZU;MURAGUCHI MASAHIRO;HIRANO AKENORI;YAMANISHI KAZUYA;TAKAHASHI MASAYUKI
分类号 A61K39/395;C12N5/10;C12N5/20;C12N15/02;C12N15/06;C12P21/08;C12R1/91;G01N33/53;G01N33/577 主分类号 A61K39/395
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