发明名称 |
HUMAN M-CSF ANTIBODY AND DETERMINATION OF HUMAN M-CSF |
摘要 |
<p>PURPOSE:To provide the subject new antibody specifically reacting with human macrophage colony stimulation factor and capable of accurately determining the factor in a specimen in high sensitivity even at a low concentration. CONSTITUTION:The objective antibody specifically reacts with human macrophage colony stimulation factor (human M-CSF). The antibody can be produced by immunizing a mammal such as mouse with human M-CSF (derivative) as an immunogen, fusing the plasmacytic cell (preferably spleen cell) of the immunized animal to a plasmacytoma cell of a mammal to form a hybridoma, selecting a clone producing the desired antibody from the hybridoma and cultivating the clone.</p> |
申请公布号 |
JPH0595794(A) |
申请公布日期 |
1993.04.20 |
申请号 |
JP19910324972 |
申请日期 |
1991.10.04 |
申请人 |
OTSUKA PHARMACEUT CO LTD |
发明人 |
OMOTO YASUKAZU;MURAGUCHI MASAHIRO;HIRANO AKENORI;YAMANISHI KAZUYA;TAKAHASHI MASAYUKI |
分类号 |
A61K39/395;C12N5/10;C12N5/20;C12N15/02;C12N15/06;C12P21/08;C12R1/91;G01N33/53;G01N33/577 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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