| 摘要 |
<p>Compounds of formula (I), wherein Q1 represents an aryl group; the dotted line represents an optional covalent bond; one of X and Y represents H and the other represents hydroxy or C¿1-6?alkoxy, or X and Y together form a group =O or =NOR?5¿ where R5 is H or C¿1-6?alkyl; Z represents O, S or NR?2¿, where R2 is H or C¿1-6?alkyl; W represents a bond or a saturated or unsaturated hydrocarbon chain of 1, 2, 3, 4, 5 or 6 carbon atoms; R?1¿ represents H or C¿1-6?alkyl. R?3¿ represents H, C¿1-6?alkyl or C2-6alkenyl; R?4¿ represents an optionally substituted phenyl group; and R6 represents a specified amino group or an optionally substituted aromatic or non-aromatic azacyclic or azabicyclic group; and salts and prodrugs are tachykinin receptor antagonists.</p> |
