发明名称 |
NOVEL ALTERNATIVE SPLICE TRANSCRIPTS FOR MHC CLASS I RELATED CHAIN ALPHA (MICA) AND USES THEREOF |
摘要 |
The present invention relates to novel alternative splice transcripts (AST) for MICA (MHC class I related chain alpha) encoding novel MICA protein isoforms and uses thereof. In particular, the present invention relates to an isolated polypeptide at least 80% of identity with a sequence selected from the group consisting of SEQ ID NO:1 (MICA-A), SEQ ID NO:2 (MICA-B1), SEQ ID NO:3 (MICA-B2); SEQ ID NO:4 (MICA-C) and SEQ ID NO: (MICA-D). |
申请公布号 |
US2016176943(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
US201414902615 |
申请日期 |
2014.07.04 |
申请人 |
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ;UNIVERSITÉ DE NANTES ;CHU DE NANTES |
发明人 |
CHARREAU Beatrice;GERARD Nathalie;TONNERRE Pierre;GAVLOVSKY Pierre-Jean |
分类号 |
C07K14/74;G01N33/68;C12Q1/68 |
主分类号 |
C07K14/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Paris FR |