ANTAGONISTS OF PROSTAGLANDIN EP3 RECEPTOR

摘要

Provided herein are antagonists of prostaglandin EP3 receptor, processes to make said antagonists, and methods comprising administering said antagonists to a mammal in need thereof.

主权项

1. A compound of Formula I: wherein m is 1 or 2; n is 0, 1, or 2; X and Y are nitrogen or CR2, provided that when X is nitrogen, Y is CR2 and further provided that when X is CR2, Y is nitrogen; R1 is H, C1-6alkyl, or C3-6cycloalkyl; R2 is H, halogen, C1-6alkyl, or C3-6cycloalkyl, wherein alkyl may be substituted with up to 3 halogens; and Each R3 is independently halogen, C1-6alkyl, or C3-6cycloalkyl, wherein alkyl may be substituted with up to 3 halogens; or a pharmaceutically acceptable salt thereof, or a solvate of said compound or salt thereof.