| 发明名称 |
Gyrase inhibitors and uses thereof |
| 摘要 |
The present invention relates to compounds of the formula I: or a pharmaceutically acceptable derivative or prodrug thereof. The compounds are useful as inhibitors of bacterial gyrase activity. The present invention also relates to methods for treating bacterial infections in mammala. The present invention also relates to methods for decreasing bacterial quantity in a biological sample.
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| 申请公布号 |
USRE40245(E1) |
申请公布日期 |
2008.04.15 |
| 申请号 |
US20040833995 |
申请日期 |
2004.04.28 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
GRILLOT ANNE-LAURE;CHARIFSON PAUL S.;STAMOS DEAN;LIAO YUSHENG;BADIA MICHAEL C.;TRUDEAU MARTIN |
| 分类号 |
C07D235/32;C07D403/04;A61K31/00;A61K31/4184;A61K31/423;A61K31/4245;A61K31/437;A61K31/4412;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/506;A61K31/5377;A61K31/55;A61K45/06;A61P31/00;A61P31/04;A61P43/00;C07D213/00;C07D221/00;C07D235/00;C07D235/30;C07D263/58;C07D401/04;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/04;C07D405/14;C07D409/04;C07D413/04;C07D471/04;C07D471/14;C07D491/04;C07D491/056;C07D498/04;C07D521/00;C07F9/6558;C07F9/6561 |
主分类号 |
C07D235/32 |
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