| 发明名称 |
STABILIZED PENTOSAN POLYSULFATE (PPS) FORMULATIONS AND METHODS OF ANALYZING THEM |
| 摘要 |
<p>Various pentosan polysulfate (PPS) formulations useful for treatment of osteoarthritis, interstitial cystitis, and other conditions of mammals are provided. These formulations showed improved resistance to degradation and discoloration and improved stability at physiological pH, even after sterilization. Capillary electrophoresis analysis of these formulations indicates that various formulations remain stable under conditions that caused degradation of PPS in prior art PPS formulations.</p> |
| 申请公布号 |
EP2010220(A2) |
申请公布日期 |
2009.01.07 |
| 申请号 |
EP20070754571 |
申请日期 |
2007.04.03 |
| 申请人 |
NUTRAMAX LABORATORIES, INC. |
发明人 |
ELLINGHUYSEN, JERRY, A.;FILBURN, CHARLES;GRIFFIN, DAVID;HENDERSON, TODD, R. |
| 分类号 |
A61K47/26;A61K31/737;A61K47/02;A61K47/12;A61K47/14;A61K47/18;A61K47/36;A61P7/02;A61P9/10;A61P9/14;A61P13/10;A61P19/02;A61P31/18 |
主分类号 |
A61K47/26 |
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