Drug delivery apparatus and method for automatically reducing drug dosage

摘要

A drug delivery device which includes a fluid drug reservoir, a catheter, a controllable fluid transfer device, e.g., a pump mechanism or valve, and a drug delivery control means: The drug delivery control means comprises a controller, e.g., a microprocessor or microcontroller which is operable to automatically reduce the rate of drug delivery over a certain reduction interval (e.g., multiple days) from an initial dosage value to a final dosage value.

主权项

1. A method delivering drug with a drug delivery device located entirely within a patient, the method comprising the steps of:
wirelessly receiving delivery data with the drug delivery device located entirely within the patient; and without receiving additional delivery data
(1) supplying drug to the patient for a period of at least 2 hours in accordance with a first stored delivery profile that includes a plurality of delivery times and a plurality of first delivery rates that correspond to the delivery times;(2) after step (1), supplying drug to the patient for a period of at least 2 hours in accordance with a second stored delivery profile that includes a plurality of delivery times and a plurality of second delivery rates that correspond to the delivery times and are respectively lower than the first delivery rates, and(3) after step (2), supplying drug to the patient for a period of at least 2 hours in accordance with a third stored delivery profile that includes a plurality of delivery times and a plurality of third delivery rates that correspond to the delivery times and are respectively lower than the second delivery rates.