发明名称 PHARMACEUTICAL COMPOSITIONS COMPRISING DIMETHYL FUMARATE
摘要 Pharmaceutical compositions are described comprising (a) dimethyl fumarate, (b) a diluent selected from monosaccharides, disaccharides, starch, and starch derivatives, calcium and magnesium inorganic salts, sugar alcohols, and mixtures thereof, (c) microcrystalline cellulose and (d) croscarmellose sodium, wherein the dimethyl fumarate is not covered with a gastro-resistant coating. These compositions are intended for the treatment of some inflammatory autoimmune diseases or disorders.
申请公布号 US2016310457(A1) 申请公布日期 2016.10.27
申请号 US201415103465 申请日期 2014.12.05
申请人 Almirall, S.A 发明人 PLANELLS JIMENEZ Maria;DUARTE LOPEZ Begoña;GUIRO COLL Pere
分类号 A61K31/225;A61K9/20 主分类号 A61K31/225
代理机构 代理人
主权项 1. A pharmaceutical composition comprising (a) dimethyl fumarate: (b) a diluent chosen from monosaccharides, disaccharides, starch and starch derivatives, calcium and magnesium inorganic salts, sugar alcohols, and mixtures thereof; (c) microcrystalline cellulose; and (d) croscarmellose sodium; wherein the dimethyl fumarate is not covered with a gastro-resistant coating
地址 Barcelona ES