发明名称 |
PHARMACEUTICAL COMPOSITIONS COMPRISING DIMETHYL FUMARATE |
摘要 |
Pharmaceutical compositions are described comprising (a) dimethyl fumarate, (b) a diluent selected from monosaccharides, disaccharides, starch, and starch derivatives, calcium and magnesium inorganic salts, sugar alcohols, and mixtures thereof, (c) microcrystalline cellulose and (d) croscarmellose sodium, wherein the dimethyl fumarate is not covered with a gastro-resistant coating. These compositions are intended for the treatment of some inflammatory autoimmune diseases or disorders. |
申请公布号 |
US2016310457(A1) |
申请公布日期 |
2016.10.27 |
申请号 |
US201415103465 |
申请日期 |
2014.12.05 |
申请人 |
Almirall, S.A |
发明人 |
PLANELLS JIMENEZ Maria;DUARTE LOPEZ Begoña;GUIRO COLL Pere |
分类号 |
A61K31/225;A61K9/20 |
主分类号 |
A61K31/225 |
代理机构 |
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代理人 |
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主权项 |
1. A pharmaceutical composition comprising (a) dimethyl fumarate: (b) a diluent chosen from monosaccharides, disaccharides, starch and starch derivatives, calcium and magnesium inorganic salts, sugar alcohols, and mixtures thereof; (c) microcrystalline cellulose; and (d) croscarmellose sodium; wherein the dimethyl fumarate is not covered with a gastro-resistant coating |
地址 |
Barcelona ES |