发明名称 |
Generation of packaging system for human recombinant adenoviral vectors |
摘要 |
The invention discloses novel means and methods for the generation of adenovirus vector. One method of the invention entails a method for generating an adenovirus vector comprising welding together two nucleic acid molecules whereby said molecules comprise partially overlapping sequences capable of combining with each other allowing the generation of a physically linked nucleic acid comprising at least two functional adenovirus inverted terminal repeats, a functional encapsulation signal and a nucleic acid of interest or functional parts, derivatives and/or analogues thereof. The invention further discloses nucleic acid molecules for generation adenovirus vectors. |
申请公布号 |
AU3445899(A) |
申请公布日期 |
1999.11.16 |
申请号 |
AU19990034458 |
申请日期 |
1999.04.23 |
申请人 |
INTROGENE B.V. |
发明人 |
RONALD VOGELS;ABRAHAM BOUT |
分类号 |
C12N15/09;A61K48/00;C07K14/075;C12N5/10;C12N7/00;C12N7/01;C12N15/861;C12R1/01 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|