| 摘要 |
A composition comprising at least one thyroid hormone compound or thyroid hormone-like compound, a hydrophilic phase-forming component, an amino alcohol and at least two emulsifying or emollient excipients selected from the group consisting of mineral oil, C12-C24 alcohols, C12-C24 carboxylic acids, C1-C8 branched or linear alkyl esters of C12-C24 carboxylic acids, glyceryl esters of C12-C24 carboxylic acids, macrogol ethers, polyethylene glycol esters of C12-C24 carboxylic acids, sorbitan esters of C12-C24 carboxylic acids (Span compounds) and polyoxyethylenated sorbitan esters of C12-C24 carboxylic acids (Tween compounds). A preferred thyroid hormone or thyroid hormone-like compound is triiodothyroacetic acid (TriAc; 4-(4-hydroxy-3-iodophenoxy-3,5-diiodophenyl)acetic acid) and a preferred amino alcohol is triethanolamine. |
