The present invention relates to novel therapies and treatments of atherosclerotic diseases. Accordingly there is provided, methods of treating or preventing atherosclerosis by passive vaccination through administration to a patient of a human antibody that is capable of binding to the specific fragments of ApoCIII. Specific human monoclonal antibodies and their use in therapy of atherosclerosis is provided. There is further provided the use of the antibodies of the present invention in medicine.
申请公布号
WO2004081046(A2)
申请公布日期
2004.09.23
申请号
WO2004EP02640
申请日期
2004.03.11
申请人
GLAXOSMITHKLINE BIOLOGICALS S.A.;BIOINVENT INTERNATIONAL A.B.;METTENS, PASCAL;MEYKENS, RENE;MONTEYNE, PHILIPPE;SCHIOETT, TORBJOERN;STRANDBERG, LEIF