| 发明名称 |
METHODS FOR DIAGNOSING CHRONIC VALVULAR DISEASE |
| 摘要 |
The invention provides methods for diagnosing chronic valvular disease in an animal. The methods comprise obtaining a sample from the animal; analyzing the sample for an amount of a microRNA (miRNA) associated with chronic valvular disease; comparing the amount of the miRNA identified in the sample to a corresponding amount of the miRNA present in a sample from one or more comparable control animals that do not suffer from chronic valvular disease; and diagnosing the animal with chronic valvular disease if the amount of the miRNA found in the animal's sample is differentially expressed in the control animal's sample. |
| 申请公布号 |
US2016237495(A1) |
申请公布日期 |
2016.08.18 |
| 申请号 |
US201615015318 |
申请日期 |
2016.02.04 |
| 申请人 |
NESTEC SA |
发明人 |
Li Qinghong |
| 分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for diagnosing chronic valvular disease in an animal comprising:
a. obtaining a biological sample from the animal; b. analyzing the biological sample for an amount of a microRNA (miRNA) associated with chronic valvular disease; c. comparing the amount of the miRNA identified in the sample to a corresponding amount of the miRNA present in a sample from one or more comparable control animals that do not suffer from chronic valvular disease; and d. diagnosing the animal with chronic valvular disease if the amount of the miRNA found in the animal's sample is greater than the amount of the miRNA present in the control animal's sample. |
| 地址 |
Vevey CH |
