| 发明名称 |
MULTILAYER TYPE PATCH |
| 摘要 |
A multilayer-type patch comprising: a support layer; a drug reservoir layer; and an adhesive layer, wherein
the drug reservoir layer comprises at least one drug selected from the group consisting of rivastigmine and pharmaceutically acceptable salts thereof, and a hydroxy group-containing acrylic-based polymer (A),the adhesive layer comprises at least one acrylic-based polymer (B) selected from the group consisting of carboxy group-containing alkyl (meth)acrylate copolymer and acrylic acid homopolymer, and a rubber-based adhesive base agent,a content of the drug in the drug reservoir layer in terms of rivastigmine in free form is 15 to 45% by mass relative to a total mass of the drug reservoir layer, anda total content of the acrylic-based polymer (B) in the adhesive layer is 7 to 18% by mass relative to a total mass of the adhesive layer. |
| 申请公布号 |
US2016374956(A1) |
申请公布日期 |
2016.12.29 |
| 申请号 |
US201415103449 |
申请日期 |
2014.12.10 |
| 申请人 |
HISAMITSU PHARMACEUTICAL CO., INC. |
发明人 |
SHINODA Tomohiro;MICHINAKA Yasunari |
| 分类号 |
A61K9/70;A61K47/32;A61K31/325 |
主分类号 |
A61K9/70 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A multilayer-type patch, comprising:
a support layer; a drug reservoir layer; and an adhesive layer, wherein the drug reservoir layer comprises at least one drug selected from the group consisting of rivastigmine and pharmaceutically acceptable salts thereof, and a hydroxy group-containing acrylic-based polymer, the adhesive layer comprises at least one acrylic-based polymer selected from the group consisting of carboxy group-containing alkyl (meth)acrylate copolymer and acrylic acid homopolymer, and a rubber-based adhesive base agent, a content of the drug in the drug reservoir layer in terms of rivastigmine in free form is 15 to 45% by mass relative to a total mass of the drug reservoir layer, and a total content of the acrylic-based polymer in the adhesive layer is 7 to 18% by mass relative to a total mass of the adhesive layer. |
| 地址 |
Tosu-shi JP |
