发明名称 |
Compositions and methods for the treatment of periodontitis and rheumatoid arthritis |
摘要 |
The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, and methods for the treatment of periodontitis and rheumatoid arthritis may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. |
申请公布号 |
US9434729(B2) |
申请公布日期 |
2016.09.06 |
申请号 |
US201314399177 |
申请日期 |
2013.05.13 |
申请人 |
CELLIX BIO PRIVATE LIMITED |
发明人 |
Kandula Mahesh |
分类号 |
A61K31/194;A61K31/198;A61K31/202;A61K31/42;A61K31/425;A61K31/4439;A61K31/455;A61K31/522;A61K31/618;C07D473/04;A61K47/48 |
主分类号 |
A61K31/194 |
代理机构 |
Raj Abhyanker, P.C. |
代理人 |
Raj Abhyanker, P.C. |
主权项 |
1. A compound of Formula I: or a pharmaceutically acceptable salt, hydrate, solvate, enantiomer, or stereoisomer thereof, wherein:R1 represents —CH2—, —CH2O—,R2 represents D, a is 2, 3 or 7; each b is independently 3, 5 or 6; e is 1, 2 or 6; c and d are each independently H, D, —OH, —OD, C1-C6-alkyl, —NH2 or —COCH3; and n is 0, 1, 2, 3, 4 or 5. |
地址 |
Hyderabad, Telangana IN |