发明名称 |
ANTISENSE MODULATION OF INHIBITOR-KAPPA B KINASE-ALPHA EXPRESSION |
摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of Inhibitor-kappa B Kinase-alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Inhibitor-kappa B Kinase-alpha. Methods of using these compounds for modulation of Inhibitor-kappa B Kinase-alpha expression and for treatment of diseases associated with expression of Inhibitor-kappa B Kinase-alpha are provided.</p> |
申请公布号 |
EP1131107(A1) |
申请公布日期 |
2001.09.12 |
申请号 |
EP19990937385 |
申请日期 |
1999.07.22 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MONIA, BRETT, P.;COWSERT, LEX, M. |
分类号 |
A61K38/00;C12N15/113;(IPC1-7):A61K48/00;C07H21/04;C07H21/02;C12Q1/68 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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