Process for the preparation of imidazo[4,5-c]-quinolin-4-amines

摘要

The present invention is a method for preparing a compound of the formula wherein R is hydrogen, C₁ to C₆ alkyl, C₁ to C₆ alkoxy or halo, R₁ and R₂ are independently hydrogen, C₁ to C₁₀ alkyl, C₁ to C₁₀ alkoxy, C₃ to C₁₀ cycloalkyl, C₃ to C₁₀ alkenyl, C₅ to C₁₀ cycloalkenyl, C₂ to C₁₀ alkynyl, C₆ to C₂₀ aryl or substituted C₆ to C₂₀ aryl and n is the integer 1 or 2 by reacting the corresponding N-oxide with an aqueous solution of ammonia and a C₁ to C₆ alkyl, C₆ to C₂₀ aryl or substituted C₆ to C₂₀ aryl chloroformate thereby forming said compound formula (1).