| 摘要 |
<p>Excellent -secretase inhibitors are provided, which contain compounds of the general formula (I) or salts thereof, wherein Ar is an aromatic group; X is a divalent group selected from among O-, -S-, -CO-, -SO-, -SO2-, -NR8-, -CONR8-, -SO¿2NR?8- and -COO- (wherein R8 is hydrogen or the like), a divalent C¿1-6? aliphatic hydrocarbon group which may contain one or two of these divalent groups, or a free valency; Y is a divalent group selected from among O-, -S-, -CO-, -SO-, -SO2-, -NR?8¿-, -CONR8-, -SO¿2NR?8-, and COO-, or a divalent C¿1-6? aliphatic hydrocarbon group which may contain one or two of these divalent groups ; R?1 and R2¿ are each hydrogen, a hydrocarbon group, or the like; and A is a ring which may be further substituted.</p> |
