发明名称 Pharmaceutical formulation comprising a phosphodiesterase inhibitor
摘要 Pharmaceutical formulations to be administered by pressurized metered dose inhalers (pMDIs), comprising a compound of general formula (I) may be used for the treatment and/or prevention of inflammatory or obstructive airway diseases.
申请公布号 US9358224(B2) 申请公布日期 2016.06.07
申请号 US201113195903 申请日期 2011.08.02
申请人 CHIESI FARMACEUTICI S.p.A. 发明人 Bonelli Sauro;Losi Elena;Zambelli Enrico
分类号 A61K9/12;A61K31/435;C07D211/82;A61K31/44;A61K9/00 主分类号 A61K9/12
代理机构 Oblon, McClelland, Maier & Neustadt, L.L.P. 代理人 Oblon, McClelland, Maier & Neustadt, L.L.P.
主权项 1. A pharmaceutical formulation for aerosol administration, comprising: (a) the (−) enantiomer of 3-cyclopropylmethoxy-4-methanesulfonylaminobenzoic acid 1-(3-cyclopropylmethoxy-4-difluoromethoxyphenyl)-2-(3,5-dichloro-1-oxypyridin-4-yl)ethyl ester; (b) a propellant; (c) a co-solvent; and (d) a surfactant selected from the group consisting of a PEG surfactant, a PVP surfactant, and a mixture thereof.
地址 Parma IT