发明名称 |
Pharmaceutical formulation comprising a phosphodiesterase inhibitor |
摘要 |
Pharmaceutical formulations to be administered by pressurized metered dose inhalers (pMDIs), comprising a compound of general formula (I) may be used for the treatment and/or prevention of inflammatory or obstructive airway diseases. |
申请公布号 |
US9358224(B2) |
申请公布日期 |
2016.06.07 |
申请号 |
US201113195903 |
申请日期 |
2011.08.02 |
申请人 |
CHIESI FARMACEUTICI S.p.A. |
发明人 |
Bonelli Sauro;Losi Elena;Zambelli Enrico |
分类号 |
A61K9/12;A61K31/435;C07D211/82;A61K31/44;A61K9/00 |
主分类号 |
A61K9/12 |
代理机构 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
代理人 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
主权项 |
1. A pharmaceutical formulation for aerosol administration, comprising:
(a) the (−) enantiomer of 3-cyclopropylmethoxy-4-methanesulfonylaminobenzoic acid 1-(3-cyclopropylmethoxy-4-difluoromethoxyphenyl)-2-(3,5-dichloro-1-oxypyridin-4-yl)ethyl ester; (b) a propellant; (c) a co-solvent; and (d) a surfactant selected from the group consisting of a PEG surfactant, a PVP surfactant, and a mixture thereof. |
地址 |
Parma IT |