MUC1-FC POLYPEPTIDE VACCINE AND PREPARATION METHOD AND APPLICATION THEREOF

摘要

Provided in the present invention are an MUC1-Fc polypeptide vaccine and a preparation method and an application thereof, the polypeptide vaccine set forth in the present invention comprising MUC1 antigenic polypeptides containing immunoglobulin Fc segments, the sequence of the polypeptides being shown in SEQ ID NO:1; by means of genetic engineering technology, the MUC1 antigenic polypeptides containing immunoglobulin Fc segments are built into a carrier, are expressed and purified in E. coli, and then undergo coating with carriers such as lipidosomes in order to obtain the MUC1-Fc polypeptide vaccine of the present invention.