| 发明名称 |
THREONINE-CONTAINING PROTEGRINS |
| 摘要 |
The invention is directed to antimicrobial peptides related to naturally-occurring protegrin peptides, and methods of using the peptides in a variety of contexts, including the treatment or prevention of infections, and diseases related thereto. The peptides exhibit decreased hemolytic activity against human red blood cells as compared with native PG-1 and melittin.
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| 申请公布号 |
WO9927945(A1) |
申请公布日期 |
1999.06.10 |
| 申请号 |
WO1998US25458 |
申请日期 |
1998.12.01 |
| 申请人 |
INTRABIOTICS PHARMACEUTICALS, INC. |
发明人 |
CHANG, CONWAY, C.;CHEN, JIE;LEHRER, ROBERT, I.;RADEL, PEGGY, A. |
| 分类号 |
A01N37/18;A01N43/38;A01N63/00;A61K38/00;A61P31/04;C07H21/04;C07K7/06;C07K7/08;C12N1/21;C12P21/04;(IPC1-7):A61K38/08;A61K38/10;A61K38/16;A61K38/17;C07K14/00;C07K14/47;C12N1/00;C12N5/10 |
主分类号 |
A01N37/18 |
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