发明名称 |
Assays for resistance to echinocandin-class drugs |
摘要 |
Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays. |
申请公布号 |
AU2006272568(A8) |
申请公布日期 |
2008.04.24 |
申请号 |
AU20060272568 |
申请日期 |
2006.07.26 |
申请人 |
MERCK & CO. INC.;UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY |
发明人 |
JENNIFER NIELSEN KAHN;STEVEN PARK;ROSEMARIE KELLY;DAVID S. PERLIN;STEPHEN A. PARENT;CAMERON M. DOUGLAS |
分类号 |
C12Q1/68;C07H19/00;C07H21/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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