| 摘要 |
The present invention includes a microfluidic filter and concentrator that can separate a filtrate from a fluid containing components, e.g. a suspension of particles, to be removed from the fluid at least to some extent. The filter may employ principals of tangential flow filtration, also known as cross-flow filtration. In one aspect, a microfluidic filter described herein includes at least a first, main channel and one or more secondary, filtering channels that connect to the main channel. Filtration occurs when a fluid portion of a sample that is flowed through the main channel enters one or more of the filtering channels and at least some of the components in the sample do not enter or do not flow through the secondary, filtering channels. The secondary channels may be dimensioned to inhibit flow of components through them, and/or a porous material such as a layer may be positioned to inhibit flow of components through the secondary channels.
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