| 主权项 |
1. A compound of formula (I) wherein A1 is CH or N; A2 is CH or N; A3 is —(CH2)n— or —CH2C(O)—; R1 is alkyl, cycloalkyl, alkoxy or halogen; R2 is substituted pyrrolidinyl or substituted dihydropyrrolyl, wherein substituted pyrrolidinyl and substituted dihydropyrrolyl are pyrrolidinyl and dihydropyrrolyl substituted with one or two substituents independently selected from halogen, hydroxyl, hydroxyalkyl, alkoxyalkyl and alkylfurazanylalkoxy; R3 is phenyl, substituted phenyl, substituted furazanyl, pyridinyl, substituted pyridinyl, dioxothietanyl, tetrahydrofuranyl, substituted tetrazolyl or substituted triazolyl, wherein substituted phenyl, substituted furazanyl, substituted pyridinyl and substituted triazolyl are phenyl, pyridinyl and triazolyl substituted with one or two substituents independently selected from alkyl, alkoxy, halogen, haloalkyl, alkylsulfonyl and cycloalkyl, and wherein substituted tetrazolyl and substituted furazanyl are tetrazolyl and furazanyl substituted with one substituent selected from alkyl, alkoxy, halogen, haloalkyl, alkylsulfonyl and cycloalkyl; n is 0, 1 or 2; provided that A1 and A2 are not both CH at the same time; or a pharmaceutically acceptable salt or ester thereof. |
