发明名称 |
PROCESS FOR PRODUCING LIPOSOMES WITH INCREASED RECEPTIVE CAPACITY TOWARDS FOREIGN MATERIALS TO BE ENCAPSULATED |
摘要 |
PCT No. PCT/EP91/00377 Sec. 371 Date Jun. 22, 1992 Sec. 102(e) Date Jun. 22, 1992 PCT Filed Dec. 9, 1992 PCT Pub. No. WO92/10166 PCT Pub. Date Jun. 25, 1992.Liposome vesicles are prepared containing water or very dilute solutions encapsulated therein. These "empty" liposomes are suspended in a carrier liquid containing, dispersed therein, substances of interest to be loaded into the vesicles and incubated for a period of time at temperatures above the lipids transition temperature, whereby loading by transmembrane permeation occurs in high yields. |
申请公布号 |
HUT62458(A) |
申请公布日期 |
1993.05.28 |
申请号 |
HU19920002595 |
申请日期 |
1991.12.09 |
申请人 |
SINTETICA S.A.,CH |
发明人 |
SCHNEIDER,MICHEL,CH;TOURNIER,HERVE,FR;HYACINTHE,ROLAND,FR;GUILLOT,CHRISTIAN,FR;LAMY,BERNARD,CH |
分类号 |
A61K9/00;A61K9/127;A61K47/48;A61K49/04;B01J13/02 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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