发明名称 PROCESS FOR PRODUCING AQUEOUS LIPOSOMAL SUSPENSIONS COMPRISING AN ACTIVE INGREDIENT
摘要 A process for the production of aqueous liposome suspensions containing active ingredients from a solution of a substance (substance mixture) for forming liposomes, in a lower alcohol with at most 3 carbon atoms and an aqueous phase, an active ingredient or active ingredient mixture is dissolved or suspended in the lipid solution and/or the aqueous phase. The aqueous phase is added to the alcoholic solution with mixing, the lower alcohol is removed by vacuum distillation and the liposome suspension is optionally freeze-dried.
申请公布号 HUT62457(A) 申请公布日期 1993.05.28
申请号 HU19920000235 申请日期 1991.04.04
申请人 SCHERING AG. BERLIN UND BERGKAMEN,DE 发明人 ROESSLING,GEORG,DE;SACHSE,ANDREAS,DE;SCHROETER,HANS-JOACHIM,DE;SPRENGER,CLAUDIA,DE;WAWRETSCHEK,CORNELIA,DE
分类号 A61K9/127;A61K49/00;A61K49/04;B01J13/02 主分类号 A61K9/127
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