ORAL FORMULATIONS OF AN ANTIFUNGAL AND A METHOD OF ITS PRODUCING

摘要

Preparation for oral dosing of antifungal agent, which conta ins a) itraconazole or saperconazole; b) hydroxypropyl-beta-cyclo dextrin with average molar substitution in the range from 0.3 to 3 and contents of unsubstituted beta-cyclodextrin under 5 % as a solubiliser of itraconazole or saperconazole; c) suitable acid me dium as a main liquid carrier; d) 1 to 20 % vol. of alcoholic co- solvent selected from the complex consisting of ethanol, propylen eglycol and glycerol; e) one or more pharmaceutically suitable in tensive sweeteners and one or more volume sweeteners; and f) one or more pharmaceutically suitable flavourings.