Dna gyrase inhibitor protein

摘要

The present invention discloses a protein that possesses an ability to inhibit bacterial DNA gyrase activity (DNA Gyrase-inhibiting protein; DGI); a host cell transformed by a replicable expression vector comprising a DNA that encodes DGI; a process for preparing DGI comprising culturing the same; a method for identifying a medical compound comprising assaying the action of modulating the DNA gyrase-inhibiting activity of DGI; and a method for identifying a medical compound comprising assaying the action of modulating the expression of a DGI-encoding gene.