| 摘要 |
Disclosed is a process for producing novel optically active titanium alkoxide complexes which are excellent in catalytic activity and enantio-selectivity in carbon-carbon bond forming reactions (for example, Ene reaction, hetero-Diels-Alder reaction, Aldol reaction) and have high stability. The present process comprises reacting (R),(S),(RS)-catalysts or mixtures thereof selected from among optically active or racemic titanium alkoxide complexes represented by the following general formula (1), etc.: wherein R1 represents a methyl, lower alkoxy or trihalogeno group; R2 represents a hydrogen or halogen atom; R3 represents a hydrogen atom or a methyl group; and R4 represents a lower alkyl group, or R1 and R2 may form together a cyclo ring; with chiral activators [(R),(S),(RS)-diols or mixtures thereof, but excluding reactions between a racemic modification and another racemic modification] to thereby activate exclusively one of the enantiomers.
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