| 发明名称 |
Piperidinone carboxamide indane CGRP receptor antagonists |
| 摘要 |
The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved. |
| 申请公布号 |
US9499541(B2) |
申请公布日期 |
2016.11.22 |
| 申请号 |
US201414505255 |
申请日期 |
2014.10.02 |
| 申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
Bell Ian M.;Fraley Mark;Gallicchio Steven N.;Ginnetti Anthony;Mitchell Helen J.;Paone Daniel V.;Staas Donnette D.;Wang Cheng;Zartman C. Blair;Stevenson Heather E. |
| 分类号 |
A01N43/42;A61K31/44;C07D211/00;C07D213/00;C07D215/00;C07D217/00;C07D219/00;C07D221/00;C07D471/04;A61K31/506;C07D487/04 |
主分类号 |
A01N43/42 |
| 代理机构 |
|
代理人 |
Todaro John C.;Fischer H. Eric |
| 主权项 |
1. A compound which is:or a pharmaceutically acceptable salt thereof. |
| 地址 |
Rahway NJ US |
