发明名称 COMPOSITION FOR GROWTH INHIBITION OF CANCER STEM CELLS COMPRISING EXTRACTS OF STICTA WEIGELII, OR BREVICID X OR SALT THEREOF AS AN ACTIVE INGREDIENT
摘要 The present invention relates to an anticancer supplement agent and a composition for inhibiting the growth of tumor stem cells, comprising at least any one selected from the group consisting of a Sticta weigelii extract, brevicid X, and a pharmaceutically acceptable salt of the brevicid X. The composition inhibits the expression of ALDH-1, CD133, CD44, Msi-1, Lgr-5, Bmi-1, EphB-1, GLI-1, GLI-2, and SMO, which is a marker of tumor stem cells, induces the apoptosis of the tumor stem cells, and exhibits effects in inhibiting the differentiation into cancer cells and self-regeneration of the tumor stem cells.
申请公布号 KR20160071023(A) 申请公布日期 2016.06.21
申请号 KR20140178197 申请日期 2014.12.11
申请人 INDUSTRY-ACADEMIC COOPERATION FOUNDATION OF SUNCHON NATIONAL UNIVERSITY;SUNCHEON RESEARCH CENTER FOR NATURAL MEDICINES 发明人 KIM, HAN GUN;HUR, JAE SEOUN;THANH NGUYEN THI
分类号 A61K36/09;A61K31/18;A61K31/337 主分类号 A61K36/09
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