| 发明名称 |
NOVEL BISPHOSPHONIC ACID DERIVATIVE AND APPLICATION FOR SAME |
| 摘要 |
This novel bisphosphonic acid derivative, which has a heterocyclic group containing a heterocyclic group-substituted amino group or a nitrogen atom, the acid moiety being esterified by a POM group or a n-butanoyloxymethyl (BuOM) group, and which is represented by the following general formula (1): Y-Cy-(NH)m-(CH2)n-C(X) (PO(OR1) (OR2))2 (1) (where the symbols are defined in the description) exhibits excellent direct and indirect cytopathic effect against tumor cells and virus-infected cells. |
| 申请公布号 |
WO2016098904(A1) |
申请公布日期 |
2016.06.23 |
| 申请号 |
WO2015JP85590 |
申请日期 |
2015.12.18 |
| 申请人 |
NAGASAKI UNIVERSITY;KYOTO UNIVERSITY |
发明人 |
TANAKA, YOSHIMASA;MATSUMOTO, KENJI;HAYASHI, KOSUKE;SAKAI, YUKI;MINATO, NAGAHIRO |
| 分类号 |
C07F9/6539;A61K31/663;A61K31/675;A61K47/40;A61P31/12;A61P31/16;A61P31/18;A61P31/22;A61P35/00;A61P35/02;C07F9/40;C07F9/58;C07F9/60;C07F9/6503;C07F9/6512;C07F9/6524;C07F9/653;C07F9/6561 |
主分类号 |
C07F9/6539 |
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