| 发明名称 |
METHOD FOR PREDICTION OF PREDISPOSITION TO COURSE OF POSTTRAUMATIC OSTEOARTHROSIS OF KNEE JOINT |
| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to medicine, and it is aimed at diagnosing a predisposition to posttraumatic osteoarthrosis of the knee. In the patients pleomorphism genotyping rs2276109 (A-82G) of the MMP-12 gene is performed. When revealing the GG genotype, genetic predisposition to course of posttraumatic osteoarthrosis of the knee is diagnosed.EFFECT: invention provides an increase of detection reliability of genetic individual's predisposition to course of osteoarthrosis of the knee after traumatic injury by determining the polymorphism in gene of 12 matrix metalloproteinase.1 cl, 3 ex |
| 申请公布号 |
RU2600860(C2) |
申请公布日期 |
2016.10.27 |
| 申请号 |
RU20140153254 |
申请日期 |
2014.12.25 |
| 申请人 |
Federalnoe gosudarstvennoe avtonomnoe obrazovatelnoe uchrezhdenie vysshego obrazovaniya "YUzhnyj federalnyj universitet" |
发明人 |
Vnukov Valerij Valentinovich;Panina Svetlana Borisovna;Krolevets Igor Vladimirovich;Milyutina Natalya Petrovna;Ananyan Anzhelika Arshakovna;Zabrodin Mikhail Alekseevich |
| 分类号 |
G01N33/50;C12Q1/68 |
主分类号 |
G01N33/50 |
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