| 发明名称 | Powerful MHC-class II peptides derived from survivin | ||
| 摘要 | The present invention relates to peptides, nucleic acids, and cells for use in the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses. | ||
| 申请公布号 | US9498512(B2) | 申请公布日期 | 2016.11.22 |
| 申请号 | US201213526597 | 申请日期 | 2012.06.19 |
| 申请人 | IMMATICS BIOTECHNOLOGIES GMBH | 发明人 | Rammensee Hans-Georg;Stevanovic Stefan;Gouttefanges Cecile;Weinschenk Toni;Lewandrowski Peter |
| 分类号 | C07H21/00;C12N15/86;C12N5/10;C07K14/47;A61K38/10;C07K14/705;A61K39/00;C07K7/08;C07K16/18;C12N15/10 | 主分类号 | C07H21/00 |
| 代理机构 | McBee Moore Woodward and Vanik IP LLC | 代理人 | McBee Moore Woodward and Vanik IP LLC |
| 主权项 | 1. An isolated nucleic acid sequence encoding: a peptide consisting of SEQ ID NO: 3. | ||
| 地址 | Tuebingen DE | ||