发明名称 |
Prediction and treatment of brain tumor spread using MRI and external beam radiation |
摘要 |
The invention is based on the realization that brain cancer cells spread preferentially along paths of elevated water diffusion, such as along nerve fiber bundles, that can be measured by magnetic resonance (MR) diffusion-weighted imaging (DWI) and the migration of cancer cells away from the primary tumor can be predicted using computational models that incorporate DWI information. The invention therefore applies DWI and models cell migration to develop appropriate non-symmetric margins for radiation treatment of malignant brain tumors.
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申请公布号 |
US2008051649(A1) |
申请公布日期 |
2008.02.28 |
申请号 |
US20070878639 |
申请日期 |
2007.07.25 |
申请人 |
O'DELL WALTER G;OKUNIEFF PAUL;KRISHNAN ANITHA P;ASHER ISAAC |
发明人 |
O'DELL WALTER G.;OKUNIEFF PAUL;KRISHNAN ANITHA P.;ASHER ISAAC |
分类号 |
A61B5/055 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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