| 发明名称 |
METHOD FOR OBTAINING ANTIGEN-SPECIFIC TR1 REGULATORY LYMPHOCYTES |
| 摘要 |
The invention relates to a method for preparing antigen-specific Tr1 regulatory lymphocytes. The inventive method involves the use of artificial antigen-presenting cells, expressing a molecule from the HLA class II system and a human LFA-3 molecule and expressing none of the B7-1, B7-2, B7-H1, CD40, CD23 or ICAM-1 costimulation molecules.
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| 申请公布号 |
US2008233095(A1) |
申请公布日期 |
2008.09.25 |
| 申请号 |
US20070928189 |
申请日期 |
2007.10.30 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
GROUX HERVE;COTTREZ FRANCOISE;WAKKACH ABDELILAH |
| 分类号 |
A61K48/00;C12N15/09;A61K35/14;A61K39/00;A61P3/10;A61P19/02;A61P29/00;A61P37/02;A61P37/06;C12N5/02;C12N5/0783;C12N5/10 |
主分类号 |
A61K48/00 |
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