发明名称 Prenylflavanone compounds for modulating diabetes
摘要 The present invention is directed to a novel use of prenylflavanone compounds for control of blood glucose and treatment or prevention of diabetes.
申请公布号 US9457007(B2) 申请公布日期 2016.10.04
申请号 US201414226080 申请日期 2014.03.26
申请人 NATUREWISE BIOTECH & MEDICALS CORPORATION 发明人 Chen Chia-Nan;Chi Li-Ling
分类号 A61K31/353;C07D311/32;A61K35/644 主分类号 A61K31/353
代理机构 WPAT, P.C., Intellectual Property Attorneys 代理人 WPAT, P.C., Intellectual Property Attorneys ;King Anthony
主权项 1. A method for modulating blood glucose in a subject in need thereof, comprising administering to the subject an effective amount of a compound selected from the following: (S,E)-2-(3,4-dihydroxyphenyl)-6-(3,7-dimethylocta-2,6-dien-1-yl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one (PPC) (S,E)-2-(2-(3,7-dimethylocta-2,6-dien-1-yl)-3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one (PPD) (S,E)-2-(3-(3,7-dimethylocta-2,6-dien-1-yl)-4,5-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one (PPF) (S,E)-2-(2-(3,7-dimethylocta-2,6-dien-1-yl)-3,4-dihydroxyphenyl)-5,5,7-dihydroxy-6-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one (PPG) (S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one (PPI) (S,E)-2-(3,4-dihydroxy-2-(7-hydroxy-3,7-dimethyloct-2-en-1-yl)phenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one (PPA) 10 (S,E)-2-(3,4-dihydroxy-5-(7-hydroxy-3,7-dimethyloct-2-en-1-yl)phenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one (PPB) (S,E)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-(7-hydroxy-3,7-dimethyloct-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one (Pokinawan) (S,E)-2-(3,4-dihydroxy-2-(7-hydroxy-3,7-dimethyloct-2-en-1-yl)phenyl)-5 5,7-dihydroxy-6-(3-hydroxy-3-methylbutyl)-3,4-dihydro-2H-1-benzopyran-4-oneand (S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-((2E,6E)-11-hydroxy-3,7,11-trimethyldodeca-2,6-dien-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one
地址 Taipei TW