Selective inhibition of β1-adrenergic receptors for the treatment of pediatric heart failure

摘要

Provided are methods of treating heart failure in children using B1-selective adrenergic receptor antagonists, alone or in combination with other agents, including B-2-selective adrenergic receptor agonists.

主权项

1. A method of treating dilated cardiomyopathy in a pediatric subject comprising administering to said subject an effective amount of a β1-adrenergic receptor-selective antagonist, wherein said β1-adrenergic receptor-selective antagonist is at least twice as β1-selective as Metoprolol.